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Year : 2020  |  Volume : 17  |  Issue : 4  |  Page : 275-276

Xanthogranulomatous osteomyelitis

1 Department of Pathology, Indraprastha Apollo Hospital, New Delhi, India
2 Department of Orthopedics, Indraprastha Apollo Hospital, New Delhi, India

Correspondence Address:
Seema Singhal
Department of Pathology, Indraprastha Apollo Hospital, New Delhi
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Source of Support: None, Conflict of Interest: None

DOI: 10.4103/am.am_72_19

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Xanthogranulomatous osteomyelitis (XO) is a type of chronic osteomyelitis characterized by collection of foamy macrophages admixed with mononuclear cells. Xanthogranulomatous inflammation is characterized by the presence of histiocytes, foamy macrophages, activated plasma cells, and presence of suppurative foci and hemorrhage. It has been encountered in various tissues such as gallbladder, kidney, urinary bladder, fallopian tube, ovary, vagina, prostate, testis, epididymis, colon, and appendix. Very rarely, it can affect lungs, brain, or bone. Only three cases of XO have been described previously in the literature till date.

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